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Causal interference and spillover

When one unit’s treatment changes another’s outcome, direct effects, spillovers and rollout effects differ. A paired example shows why assignment design changes the comparison.

Causal interference occurs when a unit’s outcome depends on treatments assigned to other units. A spillover effect is a causal change transmitted through those other assignments. For a quant evaluating an execution rule, a treated order could change the conditions faced by a comparison order. An untreated order would then be an exposed control.
In the potential outcomes framework, write Yi(zi,z−i)Y_i(z_i,\mathbf{z}_{-i}): own assignment is ziz_i, and z−i\mathbf{z}_{-i} collects everyone else’s. No interference would allow the latter argument to be dropped. Shared market shocks can correlate outcomes without interference; interference specifically concerns the consequences of changing another unit’s treatment. Hudgens and Halloran, §2.1 formalise this distinction through assignment-indexed outcomes.

One pair, four possible outcomes

Consider a fictional paired-order experiment, with outcome measured in score points, higher being better. Stipulate perfect treatment receipt, no effects across pairs, and the same response rule for either member:
Yi(zi,gi)=10+2zi+3gi,Y_i(z_i,g_i)=10+2z_i+3g_i,

where gi∈{0,1}g_i\in\{0,1\} is the peer’s treatment. These are model inputs, not fitted market effects:

Own treatment ziz_iPeer treatment gig_iPotential outcome
0010
1012
0113
1115

Only one cell is observed for a particular unit under its realised assignment. The table does not reveal four observed outcomes for that order, and supplies no standard error.

Different treatment effects ask different questions. Use treatment-minus-comparison signs throughout:

  • Direct effect at fixed peer exposure: Yi(1,g)−Yi(0,g)=2Y_i(1,g)-Y_i(0,g)=2.
  • Spillover at fixed own assignment: Yi(z,1)−Yi(z,0)=3Y_i(z,1)-Y_i(z,0)=3. At z=0z=0, this is the effect on an untreated unit of treating its peer.
  • Total effect, both treated versus neither: Yi(1,1)−Yi(0,0)=5Y_i(1,1)-Y_i(0,0)=5.
Here 5=(15−13)+(13−10)=2+35=(15-13)+(13-10)=2+3. The decomposition uses a specified intermediate cell. With an own–peer interaction, the direct effect could differ across peer exposures; one cannot combine arbitrary direct and spillover contrasts. These terms concern cross-unit effects; “direct” and “indirect” in mediation analysis instead distinguish causal pathways through a mediator. Hudgens and Halloran, §§3.2–3.5 define interference effects and their allocation-strategy averages.
Stipulated focal-unit outcomes: own and peer untreated 10, own only treated 12, peer only treated 13, both treated 15 score points. Holding peer fixed gives direct effect 2; holding own fixed gives spillover 3. Expected treated-minus-control contrasts are 2 under independent fair coins, minus 1 with exactly one treated per pair, and 5 with all-or-none pair assignment.
Stipulated focal-unit outcomes: own and peer untreated 10, own only treated 12, peer only treated 13, both treated 15 score points. Holding peer fixed gives direct effect 2; holding own fixed gives spillover 3. Expected treated-minus-control contrasts are 2 under independent fair coins, minus 1 with exactly one treated per pair, and 5 with all-or-none pair assignment.
Original paired-unit model. The same potential outcomes produce different treated–control comparisons because each design changes which peer exposures accompany own treatment.

The design changes the comparison

Imagine many pairs obeying that stipulated rule. Compare expected outcomes conditional on own assignment under three randomised designs:

Assignment within each pairMean if own treatedMean if own untreatedDifference
Independent fair coins(12+15)/2=13.5(12+15)/2=13.5(10+13)/2=11.5(10+13)/2=11.52
Exactly one treated, chosen fairly1213−1
Both treated or both untreated, fair choice15105
The second design makes every untreated unit’s peer treated. Its negative comparison does not mean own treatment has a negative effect holding the peer fixed. The third design varies own and peer treatment together: it compares packages, and cannot separately recover the two effects without additional assumptions. These are exact conditional expectations under the model, not guaranteed differences in a finite realised sample.
A policy or overall effect compares population means under two allocation strategies, averaging over both own and others’ assignments. In this model, a policy independently treating each unit with probability pp gives
Ep[Yi]=10+2p+3p=10+5p.\mathbb{E}_p[Y_i]=10+2p+3p=10+5p.

Changing pp from 0.250.25 to 0.750.75 changes the policy mean from 11.2511.25 to 13.7513.75: an effect of 2.52.5 points. It differs from the direct effect 22 and the all-treated-versus-none effect 55. Specify the population weights and allocation rule: “the treatment effect” alone leaves the target ambiguous.

What identification needs

An exposure mapping compresses others’ assignments into relevant exposure, for example gi=hi(z−i)g_i=h_i(\mathbf{z}_{-i}), giving Yi(zi,gi)Y_i(z_i,g_i). A treated-neighbour count assumes identities and more distant assignments do not matter beyond that count. Such compression is a substantive restriction, not a consequence of randomisation.
For design-based estimation, interventions and exposure must be well defined, observed outcomes must match the realised potential outcomes, and the assignment mechanism must be known. The exposure contrasts need positive assignment probabilities for the target units: positivity concerns the joint exposure, not only own treatment. Unequal exposure probabilities may require weighting; uncertainty must respect jointly generated exposures. Aronow and Samii, §§3–4 set out these conditions.
Cluster assignment does not automatically remove interference. Partial interference permits effects within groups while assuming none across groups. If orders in different assigned clusters interact through the same market, that assumption needs justification. Merely changing standard errors cannot turn an exposed control into an unexposed counterfactual. The Difference-in-Differences lesson examines this control-group requirement (public preview; full lesson requires membership).

Sources

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  • causal inference
  • interference
  • spillover
  • experimental design
  • potential outcomes
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